Polyvinylacetate phthalate

Schonecker DR, DeMerlis CC, Borzelleca JF. Evaluation of the toxicity of polyvinylacetate phthalate in experimental animals. Food Chem Tox 2003 41 405. 

Abbreviations. BZC, benzalkonium chloride PS, potassium sorbate CDs, cyclodextrins HP-fi-CD, 2-hydroxypropyl-p-cyclodextrin HPMCAS, hydroxypropyl methylcellulose acetate succinate PEG, polyethylene glycol P-407, poloxamer 407 PVAP, polyvinylacetate phthalate. 

Polyvinyl chloride can be shaped into clear, soft flexible tubing and sheets with the aid of using plasticizers such as diethylhexyl phthalate (DEHP). Polyvinyl chloride resins are used for children s toys, automobile seat covers, and for catheters used for intravenous transfusion of blood and nutrients in hospitals and homes. When DEHP was suspected of leaching out of the products, and of being a carcinogen, substitutions were developed with polyvinylacetate and polyethylene. However, these substitutes are not yet totally satisfactory, as they cannot be steam sterilized, and they are not as clear and flexible as PVC. 

Figure 11.40. Glass transition temperature of polyvinylacetate plasticized with dibutyl phthalate vs. plasticizer concentration. [Data from Averco-Antonovich I U Gotlib D M Chakirov R R Sokolova Y A, Macro-mol. Symp., 176, Nov. 2001, p.181-7.]...

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