Polyurethanes ventricular assist devices

Polyurethane (PEU) Artificial hearts and ventricular assist devices Catheters Pacemaker leads... 

Polyurethanes, due in part to their flexibility and toughness, are perhaps the polymer of choice for ventricular assist devices and blood pumps. Consequently, they have received considerable interest as bloodcontacting materials. In nonhuman primates, those polyurethanes, such as Pellethane , which exhibit the most hydrophobic surface chemistry produce the least platelet consumption [12]. In dogs, early platelet interactions with polyurethanes vary considerably although relationships to polymer surface chemistry remain unclear [13]. Thus while polyurethanes are chemically versatile and possess many desirable mechanical properties, it is generally not possible to predict their biologic responses in humans. 

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