Polysaccharides and Its Recent Advances In Delivering

Covalent crosslinking Ionic crosslinking Polyelectrolyte complexation 

Colon specific delivery gained inaeasing significance for the managanent colonic diseases, such as colorectal amebiasis, ulcerative colitis, Crohn s disease and cancer [34], Various approaches are used for targeting drugs to the colon include enzymatically degradable polymers  

Hyaluronic acid Animal (synovial fluid, vitreous humour of the eye, umbilical tissue microbial (fermentation Bacillus subtflis) P-glucuronic acid and N-acetyl-P-glucosamine (GlcNAc) linked by a-(l/3) bond. [35] 

Dextran Microbial (bacterium Leuconostoc mesenteroides) a-(l/6)-linked d-glucose residues with some degree of branching via a-(l/3) linkages. [36] 

GeUan gum as a repeating unit Microbial (bacterium Sphingomonas elodea) Tetrasaccharide, (l/4)-Lrhamnose--(l/3)-P-glucose—(1 /4)-P-glucuronic acid—(l/4)-d-glucose [37] 

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