Polypho sphazene

These polymers are of increasing utility and are good examples of the cellular requirement for water in tissue engineering scaffolds. Polypho-sphazenes are degradable polymers that have been functionalized with a variety of biomolecules such as peptides and growth factors. ... 

Degradable, synthetic polymers that are commonly known in the medical field include poly(a-hydroxy esters), poly(fi-caprolactone), poly(ortho esters), polyanhydrides, poly(3-hydroxy butyrate), polypho-sphazenes, polydioxanones, polyoxalates, and poly(amino acids). 

Addition of fluorine to both cyclotriphosphazenes and linear polypho-sphazenes have been found to yield significant antimicrobial behavior. Linear polyphosphazenes were formed using 4-fluoroaniline using three differing routes. Scheme 4. First, the conventional nucleophilic substitution route emplying poly[bis-chlorophosphazene] yielded the desired polymer in 87% yield. Second, 2,2,4,4,6,6-hexa (4-fluoroanilino)cyclotriphosphazene... 

Ethynylpheno g cyclophosphazene and the corresponding polypho-sphazene have been prepared. These were reacted with Co2(CO)8 to afford complexes (92a-92b) with the elimination of CO. The polymer-Co2(CO)6 complex (93), when heated at 200 °C in vacuo, loses CO completely and affords a polymer matrix that encapsulates cobalt nanoparticles. ... 

Guo, Q., Pintauro, P. N., Tang, H., and O Connor, S. (1999). Sulfonated and crosslinked polypho-sphazene-based proton-exchange membranes. J. Membr. Sci. 154, 175. 

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