Polyomavirus interstitial nephritis

Elli A, Banfi G, Battista-Fogazzi G, et al. BK polyomavirus interstitial nephritis in a renal transplant patient with no previous acute rejection episodes. J Nephrol. 2002 15 313-316. 

The frequency of polyomavirus interstitial nephritis is 3%-5% in the population of renal graft recipients. When confronted with a deterioration of renal function, the diagnosis is made based on a biopsy, showing the characteristic tubular epithelium lesions, confirmed by immunohistochemistry (simian virus-40 labeling), that are often associated with inflanunatory cell infiltration into the interstitium. PCR on blood... 

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