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Polymers slow-release drug formulation

Drug delivery - many drugs are already formulated as polymer gels for oral delivery. Small molecule based gels offer the possibility if slow release or a sudden burst of drug from a chemically triggered get-sol transition. [Pg.921]

One of the major problems encountered with dispersed systems appears during their preparation, and often results from poor water solubility of drugs leading to either a low yield in drug loading or a slow or incomplete release of the drug. In order to overcome these drawbacks, several authors have proposed the use of cyclodextrins (CyDs) in the formulation of these systems. Alternatively, CyDs themselves can be employed as raw materials for particle preparation, instead of polymers and lipids. [Pg.423]


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See also in sourсe #XX -- [ Pg.100 ]




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