Polymerization via Click Chemistry

Click processes occur through simple reaction conditions such as air/moisture insensitivity, solventless or aqueous media, readily available precursors and reagents, and simple product isolation - mostly precluding chromatographic separation (unlike most organic syntheses). The utilization of click chemistry in combination with combinatorial screening will speed up the discovery of new pharmaceuticals that our society will continue to rely upon.  

Beyond smaU-molecule drug discovery, click chemistry may also be exploited for the synthesis of polymers and supramolecular architectures. Since the overall properties of the polymer are closely related to its side groups, this technique has 

Drockenmuller, E. Chem. Commun. 2008,4138. Copyright 2008 Royal Society of Chemistry. 

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