Polymerization solubilizates

As with traditional surfactants, additives may inLuence the onset of micellization of polymeric surfactants and thus affect solubilization. These additives can include inorganic salts and sugars used to adjust isotonicity and even the solubilizate drug itself. In addition to micellization, these additives can inLuence the LCST or CP and even the structure of micelles formed. 

In the present work, orthophosphate compounds have been chosen. Orthophosphates are the most compatible with biological objects, solubilizable by organic low-molecular and polymeric species. In addition, there is the... 

In recent years, W/O microemulsions have found numerous applications as microreactors for specific reactions (for comprehensive reviews, see Refs. 94 and 95). Thus, it has been shown that hydrophilic enzymes can be solubilized without loss of enzymatic activity and used to catalyze various chemical and photochemical reactions [96,97]. Other interesting applications involve the polymerization of solubilizates in microemulsions [98] and the preparation of micro-porous polymeric materials by polymerization of single-phase microemulsions [99]. Furthermore, microemulsions have been used as microreactors for the synthesis of nanosized particles for various applications [93,95] such as metal clusters (Pt, Pd, Rh, Au) for catalysis [100,101], semiconductor clusters [102-104] (ZnS, CdS, etc.), silver halides [105], calcium carbonates, and calcium fiuoride [106]. Recently it was shown [107,108] that it is possible to use W/O microemulsions for the control of polymorphism of water-soluble organic compounds. In most of these appUcations, one or more reactants are solubilized within a microemulsion and then a reaction is initiated. Depending on its molecular structure. 

---