Polymeric medical devices

Furno F, Morley KS, Wong B, Sharp BL, Arnold PL, Howdle SM, Bayston R, Brown PD, Winship PD, Reid HJ. Silver nanoparticles and polymeric medical devices a new approach to prevention of infection Journal of Antimicrobial Chemotherapy 2004,54,1019-1024. 

The present invention provides for medical devices which are antiinfective as a resirlt of antinfective agents impregnated onto their surfaces and/or antinfective activity incorporated into their access sites. It is based, at least in part, on the discovery that certain combinations of antimicrobial agents and solvents change the surface characteristics of polymeric medical devices, thereby facilitating the retention of antimicrobial agents. It is further based on the discovery that the incorporation of antinfective polymeric inserts into the access sites of a medical device provides improved antinfective activity. 

Modelling degradation of bioresorbable polymeric medical devices... 

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