Polymer-Supported Ru-TsDPEN

Preparation of polymer-supported ru-tsdpen catalysts and their use... [Pg.89]

PREPARATION OF POLYMER-SUPPORTED RU-TSDPEN CATALYSTS AND THEIR USE FOR ENANTIOSELECTIVE SYNTHESIS OF (5)-FLUOXETlNE... [Pg.141]

As the transfer hydrogenation reactions using Ru-TsDPEN catalyst could take place in aqueous solution [108-111], the next stage was to develop a polymeric catalyst suitable for the aqueous conditions. One such example was the use of PEG as a polymer support, as reported by Xiao [112]. The PEG-supported TsDPEN 176 (Scheme 3.54) was highly effective in the Ru(II)-catalyzed transfer hydrogenation of simple ketones by sodium formate in water. The same polymeric catalyst was also effective for the same reaction by using a formic acid-triethylamine azeotrope [113]. [Pg.106]