Polymer as biomaterials

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TA Horbett, J Kost, BD Ratner. Swelling behavior of glucose sensitive membranes. In SW Shalaby, AS Hoffman, BD Ratner, TA Horbett, eds. Polymers as Biomaterials. New York Plenum Press, 1984, pp 193-207. 

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Ikada Y, Suzuki M, Tamada Y (1984) In Shalaby SW, Hoffman AS, Ratner BD, Horbett TA (eds) Polymers as Biomaterials, Plenum Publ Co, p 135... 

Candidate polymers for biomedical applications must comply with a variety of requirements characteristic of most biomaterials. These requirements arise either from the specific chemical or physical structure of the polymers (chemical, physical, and mechanical criteria) or from the physiological environment where they will be used (biological criteria). Table I summarizes major criteria for the design and selection of polymers as biomaterials. 

Successful development of crystalline, polyaxial, absorbable polyesters with modulated compliance and unique thermal properties and microtexture are expected to lead to new applications and more effective uses of absorbable polymers as biomaterial devices, which calls for highly compliant, resilient, and/or microporous forms of textile constructs, films, and foams. 

CPs designed for biomedical applications generally require good electrical conductivity, physicochemical and mechanical stability, and biocompatibility to effectively interact with biological system. A wide range of analytical techniques to characterize the feasibility of conducting polymers as biomaterials are summarized here. 

Nair LS, Laurencin CT (2007) Biodegradable polymers as biomaterials. Prog Polym Sci 32 762-798... 

L.S. Nair, C.T. Laurencin, Polymers as biomaterials for tissue engineering and controlled drug delivery, Adv. Biochem. Eng. Biotechnol. 102 (2006) 47-90. 

Hyon, S.-H., Jamshidi, K. and Ikada, Y. (1984) Melt spinning of poly-L-lactide and hydrolysis of the fiber in vitro, in Polymers as Biomaterials (eds S.W. Shalaby, A.S. Hoffman, B.D. Ratner and T.A. Horbett), Prenum Press, New York, pp. 51-65. 

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