Polyethylene glycol polymer mixed-matrix

Polyethylene glycol (PEG) is another well-known molecule used to reduce protein adsorption and/or platelet adhesion. Surface enrichment of a triblock oligomeric PEG containing additive from a polyurethane matrix was reported [54,55]. The authors used PEG as the active groups to suppress protein and platelet adhesion. The authors first synthesized a methylene diphenyl diisocyanate (MDI)-poly (tetramethylene oxide) (PTMO) 1000 prepolymer with a MW of approximately 4750 (PU4750), and then this prepolymer was terminally functionalized with mono amino-polyethylene oxide (PEG) with different MW (PEO550, 2000, or 5000, Table 2.3). This triblock copolymer was mixed with a polyurethane (MDI/ PTMO 1000/ethylene diamine (ED)) at different ratios in dimethylformamide (DMF) and cast into polymer films. The surface compositions of these films were evaluated by XPS. 

For liquid-polymer MMMs, the physical state of the fillers incorporated into the continuous polymer matrix is liquid such as polyethylene-glycol (PEG) and amines [19]. Existing literature reveals that this new type of membrane is less developed [19]. Liquid-polymer MMMs are a less commonly used mixed-matrix technology, dne to the long-term stability encapsulated in the continuous polymer matrix. A new type of MMM has recently been developed in an attempt to deal with the disadvantages of liqnid-polymer MMMs. Solids, snch as activated carbon impregnated with liquid polymer (e.g., PEG), function as stabilizers of the liquid polymer in the continuous phase. Eurthermore, activated carbon increases the MMM performance. 

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