Polydimethylsiloxane microfluidic systems

Buch, J.S., Wang, P.-C., DeVoe, D.L., Lee, C.S., Field-effect flow control in a polydimethylsiloxane-based microfluidic system. Electrophoresis 2001, 22(18), 3902-3907. 

Li S, Chen S (2003) Polydimethylsiloxane fluidic interconnects for microfluidic systems. IEEE Trans Adv Packag 26(3) 242-247... 

The most common conhguration for performing on-chip detection has been the embedded hber type of device as listed in Table 1. A typical setup, shown in Fig. 1, includes a light source and fiber for delivery, exit fiber connected to a detection system, microfluidic channel, and liquid delivery components. The fibers are usually embedded in chip materials consisting of polydimethylsiloxane (PDMS), SU-8 epoxy, polymethyl methacrylate (PMMA), or glass [3]. 

Printed circuit board (PCB) technology was employed for the fabrication of electrodes to be employed for luminol-H202 solutions. These electrodes were used with two microfluidic ECL cells that combine transparent polydimethylsiloxane (PDMS) microchannels [16]. The differences between the two cells were the working electrode size (10 mm Au vs 0.09 mm Au) and the ECL detection volume (4 pL vs 4 nL). No counter electrode was used in this system while Ag/AgCl reference electrode was obtained by electrodeposition of Ag on Au,... 

Figure 5.2 Schematic of organic excitation and detection system with microfluidic device for fluorescence detection. Green organic light-emitting diode (OLED) acts as the light source, the polydimethylsiloxane (PDMS) microfluidic chip contains the dye detection volume, and polarizer 2 is used to filter out the excitation light and allows only the emission signal to pass through to the organic photodiode (OPD).

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