Polycyclic aromatic hydrocarbons nitro-substituted

Nitro-substituted polycyclic aromatic hydrocarbons (nitro-PAHs) are formed during the combustion of fossil fuels at high temperatures with a vast supply of combustion air. In this reaction, conversion of nitrite (NO2) to nitric acid is an important intermediate step. Another source of nitro-PAHs is the photochemical radical-mediated conversions of parent PAHs to nitro-derivatives. Combustion at high temperatures with a vast supply of combustion air may lead to the formation of 1-nitropyrene (1-NP), whereas photochemical conversion of pyrene gives rise to 2- and 4-nitropyrene [24,25]. 

P.P. Fu et al., Effects of nitro substitution on the in vitro metabolic activation of polycyclic aromatic hydrocarbons, in Polycyclic Aromatic Hydrocarbon Carcinogenesis Structure-Activity Relationships, ed. by S.K. Yang, B.D. Silverman (CRC Press, Florida, 1988), pp. 37-65... 

Zimmerman, S. C., Saionz, K. W., and Zeng, Z. (1993) Chemically Bonded Stationary Phases that Use Synthetic Hosts Containing Aromatic Binding Clefts HPLC Analysis of Nitro-Substituted Polycyclic Aromatic Hydrocarbons, Proc. Natl. Acad. Set, U.S.A. 90, 1190-1193. 

Song, X.-H., Xiao, M., and Yu, R.-Q. (1994) Artificial neural networks applied to classification of mutagenic activity of nitro-substituted polycyclic aromatic hydrocarbons. Comput. Chem. 18,391-396. 

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