Polyacrylamide-silastic grafts

The radiation grafting technique used to prepare the polyacrylamide-Silastic grafts is a practical method for immobilizing the mechanically weak... 

Thrombotic Events on Grafted Polyacrylamide—Silastic Surfaces as Studied in a Baboon... 

Laser Light Scattering Detection of Microemboli. To elucidate the mechanism of platelet destruction by grafted polyacrylamide-Silastic surfaces, an optical scattering technique was developed (20) to observe and quantitate the sizes and size distributions of microaggregates in blood produced within the AV baboon shunt. Presumably, any such flowing microaggregates represent platelet microemboli. 

Figure 4. Graft level as a function of length along the shunt for polyacrylamide-Silastic shunts prepared using the flow-grafting apparatus described in Ref 14.

Figure 11. Platelet consumption vs. graft level of polyacrylamide-Silastic shunts (9). (Numbers in parentheses refer to the number of shunts tested for each value reported.)...

Title Thrombotic Events on Grafted Polyacrylamide-Silastic Surfaces as... 

A series of shunts with radiation and ceric ion-initiated grafts of polyacrylamide on the luminal Silastic surface, and having water contents varying between 51-83% were also studied. Table III shows these data. The platelet consumption increases linearly with the gel water, such that the ratio of platelet consumption to graft water content remains relatively constant. 

Exposed Area (cm2) Mean Platelet Survival Time (days) Cannula Platelet Consumption (platelets/day x 10 10) Polyacrylamide-grafted Silastic Cannula Platelet Consumption/ Unit Area (platelets/cm2 day x 10 H)... 

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