Poly -pyrene synthesis

Winnik FM, Adronov A, Kitano H. Pyrene-labeled amphiphihc poly-(iV-isopropylacrylamides) prepared by using a lipophific radical initiator synthesis, solution properties in water, and interactions with hposomes. Can J Chem 1995 73 2030—2040. 

The literature for peptide-membrane interactions is both vast and well covered. For the purposes of this chapter, we will look only at polymers - molecules made from polymerization reactions rather than solid-state synthesis or extracted from living organisms - made from a- and p-amino acids. Yaroslavov et al examined binding between poly-a-r-lysine (PLL) and anionic vesicles. SUVs of lecithin and cardiolipin were labeled with pyrene and exposed to PLL (Cl6) (Figure 21). The decrease in pyrene fluorescence indicated that PLL binds to the vesicles. Saturable binding was observed. The addition of high concentrations of salt or low... 

Figure 6.8 Synthesis of different tetragonal 2D COFs by co-condensation of phthalocyanine with various linkers [ly, pyrene NDI, naphthalene diimide PPE, poly(phenylene ethynylene)].

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