Poly L-Lactide Degrading Enzymes

Involvement of enzyme in the degradation of PLLA has been controversial. Some studies argue in favor of enzymatic degradation, while others consider the nonenzymatic involvement of PLLA hydrolysis in natural environments. Enzymes play a significant role in the degradation of PLLA, although they are not solely responsible for the hydrolysis of PLLA. 

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Jarerat, A., Tokiwa, Y. and Tanaka, H. (2004) Microbial poly(L-lactide)-degrading enzyme induced by amino acids, peptides and poly(L-amino acids). Journal cf Polymers and the Environment, 12, 139-146. 

Pranamuda, H., Tsnchii, A. and Tokiwa, Y. (2001), Poly(L-lactide)-degrading enzyme prodnced hy Amycolatopsis sp. , Macromol. Biosci. 1 (1), 25-29. 

Dong, J., Liao, L., Ma, Y., Shi, L., Wang, G.X., Fan, Z., Li, S., Lu, Z., 2014a. Enzyme-catalyzed degradation behavior of L-lactide/trimethylene carbonate/glycolide terpolymers and a composite with poly(L-lactide-co-glycolide) fibers. Polymer Degradation and Stability 103, 26-34. 

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