Poisons admissible levels

Neuroleptic drug poisoning in 86 children has been retrospectively studied in two pediatric hospitals in the USA (1987-1997), with about 9000 and 11 000 annual admissions (617). Most (70%) occurred in children under 6 years of age over two-thirds of the cases (78%) were unintentional. The owner of the medication, when identified (85% of cases), was the grandmother (22%), another family member (21%), the patient (13%), or a non-family caregiver (8%) the most common places where ingestion occurred were the patient s home (64%) or a relative s home (22%). There was a depressed level of consciousness in 91% and a dystonic reaction in 51% there were no deaths. 

Ro. 17. Plasma GST B and B2 subunits and ALT activities in patients with paracetamol poisoning. The upper (a) figure shows enzyme levels in patients treated successfully with Af-acetylcysteine following the admission (first) blood sample and the lower (b) figure the enzyme levels in patients admitted too late after the overdose for effective treatment with Af-acetylcysteine. All data are expressed as multiples of the upper reference limit. 

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