Podopetalum ormondii

Ormosia Group.—An alkaloid obtained from Podopetalum ormondii was shown to have structure (18) by X-ray analysis and is thus epimeric with podopetaline at C-6 12 the same structure was assigned to amazonine, isolated from Ormosia amazonia, but it has not yet been possible to establish the identity of the two alkaloids. 

A number of unusual quinolizidine alkaloids have been isolated from various leguminous plants now classified in the Fabaceae, such as lamprolobine (59) from Lamprolobium fruticosum 182], and podopetaline (60), a new member of the Ormosia group of alkaloids that was isolated from Podopetalum ormondii [831. Other genera, including Templetonia and Hovea, have been found to produce well-known leguminous alkaloids such... 

The structures of two new hexacyclic alkaloids of Ormosia costulata have been determined by X-ray crystallography. One alkaloid is an enantiomer of the optically inactive j amine (20), and is reported to be identical with a formaldehyde adduct of an alkaloid of Podopetalum ormondii jamine was shown previously to be a constituent of O. panamensis and O. jamaicensis. A second new optically active alkaloid (21), homodasycarpine, is a stereoisomer of jamine. Absolute stereochemistry has not been established, and is not implied in structures (20) and (21). 

---