Pluchea

Sesquiterpenoids isolated form Pluchea indie, Hibiscus tiliaceus, and Thespesia populnea were given full attention. Most sesquiterpenoids isolated form Pluchea indie were eudesmane and eremophilane diterpenoid skeleton, For example, the compounds were depicted in Figure 4. 

Figure 4. Structures of sesquiterpene ids from Pluchea indica...

Wang, J. Chemical constituent investigation of Mangrove Plant Pluchea Indica (T.) [D]. Master s thesis of Shenyang Pharmaceutical University, (2008). 

Neolupenol (lup-12-en-3p-ol) 274 Pluchea lanceolata (Compositae) stem and leaves CAR [167]... 

Ahmad VU, Khatvon R (1995) Two New Sesquiterpenes from Pluchea arguta. Sci Pharm 63 231... 

Ahmed AA, El-Seedi HR, Mahmoud AA, El-Aziz A El-Douski A, Zeid IF, Bohlin L (1998) Eudesmane Derivatives from Laggera crispata and Pluchea carolonesis. Phytochemistry 49 2421... 

Inderjit and Dakshini, K.M.M. Allelopathic potential of the phenolics from the roots of Pluchea lanceolata. Physiol Plant 1994 92 571-576. 

Bohlmann has isolated another naturally occurring thymol epoxy-ester (c/. Vol. 1, p. 34 Vol. 3, p. 46), this time from Wedelia forsteriana Compound (137)has been isolated from Pluchea odorata. Pseudomonas fluorescens converts (-)-menthone into cis- and trans-(138). In addition to known (Vol. 2, p. 31) p-menthane-8-thiol-3-ones in Buchu leaf oil, 5-methyl dnd S-acetyl derivatives have been isolated... 

Dasgupta B Basu K Dasgupta S Chemical investigation of Pluchea lanceolata. II. Identity of pluchine with betaine hydrochloride. In Experientia (1968 Sep 15) 24(9) 882 ISSN 0014-4754. 

The racemic form of a new sesquiterpenoid, voleneol diacetate (394), has been identified as a constituent of the stem bark of Lepidotrichilia volensii Leroy. Several new eudesmane derivatives have been isolated from various species of Verbesina and their structures, (395)—(398), determined by spectroscopic methods.Related investigations have shown that cuauhtemone (399) (Vol. 5, p. 74) and the eudesmane derivative (400) are metabolites of Pluchea foetida while y-selinen-8-one (401) occurs in the roots of Peteravena schultzii ... 

Scholz, E., Heinrich, M., and Hunkier, D. (1994). Caffeoylquinic acids and some biological activities of Pluchea symphytifolia. Planta Med. 60, 360-364. 

Among the plant terpenoids with a lupane skeleton, lupeol is the simplest one and has recently been reported as the active principle of Crataeva religiosa (Capparidaceae). When it was tested on the habitual models of inflammatory response, it showed moderate activity on the carrageenan-induced rat hind paw and rat pleurisy [61]. A compound with a related structure is moretenol acetate, which was the most active of the triterpenes from Pluchea lanceolata (Asteraceae). When administered 50 mg/kg p.o., it inhibited by 55% the edema caused 3.5 h after carrageenan injection into rat hind paw [62]. At 100 mg/kg p.o. neolupenol, from the same plant, reached 55% inhibition at 2.5 h and 70% inhibition at 5 h [63]. 

Chemical investigation of Pluchea arauta led to the isolation of ten new sesquiterpenes of eudesmane type. These are arguticin... 

Constit. of Pluchea symphytifolia (Asteraceae). Yellowish-white amorph. powder, [a] —175 (c, 2 in MeOH). [158364-85-3, 158414-91-6]... 

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