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Platelet activation myosin light chain

Hathaway, D.R. Adelstein, R.S. Human platelet myosin light chain kinase requires the calcium-binding protein calmodulin for activity. Proc. Natl. Acad. Sci. USA, 76, 1653-1657 (1979)... [Pg.46]

NAKA M, NISHKAWA M, ADELSTEIN RS, HDAKA H. Phorbol ester-induced activation of human platelets is associated with protein kinase C pho horylation of myosin light chains. Nature306 490-492,1983. [Pg.230]

The increase in cGMP activates the cyclic-dependent protein kinase (PKG), which reduces the intracellular concentration of calcium and activates the myosin light chain phosphatase (MLCP), leading to relaxation of the vascular smooth muscle. In addition, NO can also exert a large number of effects such as inhibition of platelet adhesion and aggregation, smooth muscle prohferation, monocyte adhesion, as well as activation of glucose uptake, glycolysis, and fatty acid oxidation (for reviews, see [23, 37]). [Pg.2365]

See other pages where Platelet activation myosin light chain is mentioned: [Pg.3680]    [Pg.607]    [Pg.136]    [Pg.267]    [Pg.237]    [Pg.405]    [Pg.53]    [Pg.191]    [Pg.198]    [Pg.217]    [Pg.426]    [Pg.119]    [Pg.271]    [Pg.214]    [Pg.220]    [Pg.366]    [Pg.452]   
See also in sourсe #XX -- [ Pg.199 ]



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Light chain

Light chains myosin

Light-activation

Myosin

Myosin activation

Myosin chains

Myosin light

Platelets activation

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