Plaque rupture pathophysiology

Shah PK. Pathophysiology of plaque rupture and the concept of plaque stabilization. Cardiol Clin. 2003 21 303-314. 

Schroeder AR Falk E. Pathophysiology and inflammatory aspects of plaque rupture. Cardiol Clin 1996 14 21 1-220,... 

Molecular imaging may potentially address not only the pathophysiology of ischemia but also vascular inflammation causing rupture of atherosclerotic plaques before major ischemic events. Initial approaches have used imaging of "indium radiolabeled monocytes [150], upregulated metallo-proteinases [151], and imaging of apoptosis in atherosclerotic lesions [152]. However, none have evolved into clinically useful tests. 

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