Plackett Burman designs applications

Problem 2.10 The Application of a Plackett-Burman Design to the Screening of Factors Influencing a Chemical Reaction... 

Several types of designs are available, and the choice of design depends on the number of variables and how detailed the information has to be. A full factorial design is a good choice when the number of variables is four or less. When more than four variables are of interest, a fractional design is applicable. With a large number of variables, a Plackett-Burman design (PBD) [164, 165] is the preferred choice. 

Deshmukh, D. V, Puranik, P. R. Application of Plackett-Burman design to evaluate media components affecting antibacterial activity of alkaliphilic cyanobacteria isolated from Lonar Lake. Turk J Biochem. 2010,35(2), 114-120. 

In the previous sections it has been shown that the qualitative variables can be studied by those designs in which each variable has two levels (Factorial Design and Plackett-Burman Design). In real applications very often qualitative variables have more than two levels, and therefore a different design must be applied. 

A. A. Momen, G. A. Zachariadis, A. N. Anthemidis and J. A. Stratis, Optimisation and comparison of two digestion methods for multielement analysis of certified reference plant materials by ICP-AES. Application of Plackett-Burman and central composite designs, Microchim. Acta, 160(4), 2008, 397-403. 

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