Pivalyl chloride

It would thus appear that O acylation is the normal course of the acylation of enamino ketones. Surprisingly the enamino ketones 49 and 50 undergo reaction with acid chlorides not having an a-hydrogen (e.g., benzoyl and pivalyl chlorides) to give the products of C acylation (133). 

By dehydrohalogenation of /-butyl chloride, the nucleophilic isobutene, and by its reaction with carbon monoxide the electrophilic pivalyl chloride, are produced. These two reagents afford the monoacylation products 141 and 142 the unconjugated enone 142 is able to undergo a second acylation (reaction of the type in Section II, C, 1, a) leading to the pyrylium salt 142. 

Pivaloyl-1,3-indandione 2-Pivaloylindane-1,3-dione. See Pivalyl indandione Pivalyl chloride. See Pivaloyl chloride... 

Treatment of 2, 3 -(9-methoxyethylideneguanosine with pivalyl chloride and of the resulting chloro derivatives (see p, 158) with sodium methoxide furnished the 2, 3 -oxiran (427), which underwent ring-opening to give the bridged nucleoside (428). ... 

Methoxyethylideneadenosine reacted with pivalyl chloride in refluxing pyridine to give a mixture containing mainly (469) and (470), as well as the 0-(4,4-dimethyl-3-pivaloxypent-2-enoyl)(Dmpp) derivatives (471 = Cl) and... 

T etermined by gas chromatography after reaction of the cmde products with pivalyl chloride and filtration through... 

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