Piriform cortex interneurons

Marek GJ, Aghajanian GK. (1996). LSD and the phenethyiamine haiiucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex. J Pharmacol Exp Then 278(3) 1373-82. 

Sheldon PW, Aghajanian GK. 1990. Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex Evidence for the involvement of a 5-HT2-activated interneuron. Brain Res 506 62-69. 

PC also contains numerous interneurons. The distribution of GABAergic interneurons has been described for the opossum and appears to be quite similar in the rat (Haberly, personal communication). These cells are found in all layers of piriform cortex (Fig. 25), including layer I, where they may function as a feedforward inhibitory system. There have been numerous reports of neuropeptide containing neurons in olfactory cortex many of these have a morphology consistent with an interneuron, but little is known about their connections or functions. 

Sheldon, P.W and Aghajanian, G.K.. (1991) Excitatory responses to serotonin (5-HT) in neurons of the rat piriform cortex Evidence for mediation by 5-HT,c receptors in pyramidal cells and 5-HT2 receptors in interneurons. Synapse, 9, 208-218. 

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