Trichostachine from Piper trichostachyon

This section summarises recent work on alkaloids containing the pyrrolidine nucleus. A short review concerning the synthesis of this group has appeared. A variety of Labiatae plants have been screened and some of them have been shown to contain pyrrolidine alkaloids. Cuskhygrine has been found in the roots of three Datura species and stachydrine has been obtained from Capparis spinosa3 The structure of trichostachine (1) Piper trichostachyon) has been elucidated by spectral means and confirmed by synthesis. Ficine (5), an interesting flavonoid alkaloid, has been synthesised. Friedel-Crafts reaction between... 

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