Phytotoxins ophiobolins

Sesterterpenoids refers to those terpenoids having 25C skeleton compounds. Up to now, only about 40 species are isolated and indentihed from several species of plants, marine organisms, and insects. Phytotoxin ophiobolin A, a natural product inhibitor of calmodulin, is an example of sesterterpenoids. 

Both the fusicoccins and the ophiobolins have attracted much attention as phytotoxins that may be involved in plant diseases (5,... 

Ophiobolanes sesterterpene phytotoxins present in various species of Helminthosporum and Cochlio-bolus. Ophiobolin A (ophiobolin, cochliobobin, co-chliobobin A) is thought to be responsible for some of the symptoms of com blight caused by Helminlhospor-... 

Three sesterterpenes (624, 625, 626) have been isolated from the genus Cheilanthes (357, 358, 359). Cheilarinosin (624) has the same ophiobolane skeletone as the ophiobolins, which are phytotoxins produced by plant pathogens, Helminthosporium (360) and Cochliobo-lus (361). 

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