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Physiological roles carcinogenesis

Biochemical Properties and Physiological Roles of 3-Oxidized Ni-trosamines in Relation to their Carcinogenesis. [Pg.26]

Peroxides can play a physiological role in the cell but also mediate processes leading to heart disease and carcinogenesis. Fatty acid peroxidation may also be related to free radical-mediated metabolic activation of carcinogens or drugs, which lead to the initiation of carcinogenesis or cytotoxicity. Modification of membrane function as a consequence of lipid peroxidation includes imcoupling of oxidative phosphorylation... [Pg.141]

The physiological role of dihydrouridine, and, therefore, DUS, remains unknown, but it occurs throughout biology. Human DUS2 is upregulated in pulmonary carcinogenesis and inhibits the kinase activity of PKR, an interferon-induced protein kinase involved in the regulation of antiviral innate immunity. ... [Pg.63]

Cohen, S. M. (1995). Role of urinary physiology and chemistry in bladder carcinogenesis. Food Chem Toxicol 33, 715-730. [Pg.513]

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Carcinogenesis

Physiological roles

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