Physiological Characteristics of the Colon

6 A Practical Approach in the Design of Colon-specific Drug Delivery Systems [Pg.158]

Degradation of dosage form components by the enzymes of the colonic microflora [Pg.158]

Coating materials with degradable bonds including capsule shells Hydrogels and matrices consisting of cross-linked, degradable polymers [Pg.158]

Sustained release coating materials with degradable domains (pore formers) [Pg.158]

Relatively constant transit Time-dependent time in the small intestine swellable polymers of about 3 h [Pg.158]