Photografting-Photoiniferter

A two-dimensional micropatterned tissue can be easily obtained by utihz-ing the inherent differences in cell adhesiveness between different micropatterned photografted regions. This was attained by photoiniferter graft polymerization with a projection mask placed on an iniferter-derivatized surface. Since protein adsorption and cell adhesion are markedly suppressed on nonionic graft polymers, such as polyDMAm, any anchorage-dependent cells such as endothelial cell adhere and proliferate only on nonirradiated surfaces, resulting in the formation of a two-dimensional patterned tissue or cellular sheet (Fig. 24). 

SCHEME 13.14 Photograft polymerization of vinyl monomers by photoiniferter mechanism. 

N. Luo, A. T. Metiers, J. B. Hutchinson, C. N. Bowman, K S. Anseth, A methacrylated photoiniferter as a chemical basis for microlifhography micro-patterning based on photografting polymerization. Macromolecules 2003, 36, 6739-6745. 

Methacrylated Photoiniferter as a Chemical Basis for Microlithography Micropatterning Based on Photografting Polymerization, 2003,... 

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