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Photodynamic therapeutic agents

Lee K-W, Park D-K, Kim Y-Y, Shin H-J (2005) Investigation of the interface region between a porous silicon layer and a silicon substrate. Thin Solid Films 478 183-187 Lee C, Kim H, Cho Y, Lee WI (2007) The properties of porous silicon as a therapeutic agent via the new photodynamic therapy. J Mater Chem 17(25) 2648-2653 Li W, Zhao D, Haneman D (2000) Low-energy electron diffraction from heated porous silicon surfaces. Surf Sci 448 40-48... [Pg.140]

The development of new synthetic methodology has successfully enabled the investigation of structure-activity relationships (SAR) of perylenequinone agents for use in photodynamic therapy. Simplified analogs, such as (M)-96, that have potency equal to the natural product hypocrellin and superior chromophores to improve photoactivation in the therapeutic window were prepared. [Pg.179]

Photosensitizers are agents that sensitize cells to radiation in the visible and near ultraviolet region of the radiation spectrum. Therapeutic use has been made of naturally occurring psoralens to treat vitiligo and psoriasis, in so-called photodynamic therapy. With newly developed UV irradiation systems that emit high-intensity UVA radiation, the principle has been extended to the treatment of severe psoriasis, mycosis fungoides and many other skin diseases. Agents used in psoralen photochemistry (PUVA) medicine include methoxypsoralen (8-MOP), trioxysalen and other synthetic psoralens. [Pg.94]

UCN can be administered in therapeutic applications such as photodynamic therapy (PDT). This involves destruction of pathological cells and tissues using toxic oxygen species generated from dynamic interaction of a photosensitizing agent with light... [Pg.195]

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Therapeutic agent

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