Phosphorylcholine-glyceride transferase

The enzyme catalysing this reaction, phosphorylcholine-glyceride transferase (CDP-choline 1,2-diglyceride cholinephosphotransferase EC 2.7.S.2), was partially purified from liver by Weiss, Smith and Kennedy (1958), who showed that it catalyses the reverse reaction, i.e. the cytidylolysis of lecithin with the formation of CDP-choline and D-a,j8-diglyceride. 

The plasmalogenic diglyceride, prepared enzymically by the action of phospholipase C on the choline-containing phospholipid of beef heart, is defined as a D-a,/5-diglyceride in which the ester at the cx -position is replaced by an imsaturated ether. The reaction is catalysed by a choline-phosphotransferase enzyme similar to the phosphorylcholine-glyceride transferase shown to participate in the biosynthesis of lecithin (Reaction 12). A similar reaction occurs in brain (McMurray 1964b). 

Q Phosphorylcholine-glyceride transferase Q Glucan synthetase II O Galactosyl transferase... 

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