Phosphorylcholine-cytidyl transferase

CDP-choline has been characterized and synthesized (Kennedy 1956). It occurs in a number of tissues (Kennedy and Weiss 1956) including brain (Ansell and Bayliss 1961) and yeast (Bebgeb and Gimenez 1956). The properties of the enzyme phosphorylcholine-cytidyl transferase (CTP cholinephosphate cytidylyl-transferase EC 2.7.7.15) catalysing Reaction 11 have been studied by Bobken-HAGEN and Kennedy (1957), who showed that the enzyme readily catalyses the reverse reaction, i.e. the pyrophosphorolysis of CDP-choline, with the formation of phosphorylcholine and CTP. 

Morre, D. J., Nyquist, S. E., and Rivera, E., 1970, Lecithin biosynthetic enzymes of onion stem and the distribution of phosphorylcholine-cytidylic transferase among cell fractions, Plant Physiol. 45 800. 

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