Phosphorus Turnover in Cell Nuclei

Marshak (122,123) has isolated nuclei from liver and lymphoma tissue of rats weighing 150 g., and has shown that most taken up by the nuclei is present in the residue obtained after extraction with trichloroacetic acid and an ethei alcohol mixture. The phosphorus compound of the residue 

Organ Time after injection distributinii in nuclci %  

Chemical analysis of the phosphorus of the liver nuclei shows that the T content of the residual fraction makes up 81% of the total phosphorus 

Nuclear activity as a fraction of liver and lymphoma tissue activity (123). 

That the rapid accumulation of by nuclei may be attributed to mitotic activity is suggested by the following experiment carried out by Marshak (123). 

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