Phospholipid diacylglycerols

Dahlqvist, A., Stahl, U., Lenman, M., Banas, A., Lee, M., Sandager, L., Ronne, H., and Stymne, S. 2000. Phospholipid diacylglycerol acyltransferase An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol In yeast and plants. Proc. Natl. Acad. Sci., 97, 6487-6492. 

Protein kinase C (a, pi, pil, y, 5, s) Calcium, phospholipids diacylglycerols Calphostin C... 

St hl, U., Carlsson, A.S., Lenman, M., Dahlqvist, A., Huang, B., Banas, W., Banai A., Stymne, S. 2004. Cloning and functional characterization of a phospholipid diacylglycerol acyltransferase from Arabidopsis. Plant Physiol. 135 1324-1335. 

The FA from PC may be transesterified to DAG by phospholipid diacylglycerol acyltransferase (PDAT) to form TAG (Wilson, 2004 Lung Weselake, 2006). Ly-sophosphatidylcholine acyltransferase (LPCAT) can catalyze the FA exchange with acyl-CoA, contributing in this way with polyunsaturated acyl-CoA to the TAG synthesis (Lung Weselake, 2006). Finally, the formation of CDP-choline and DAG... 

Acyl-CoA-independent processes have been identified that depend on either phosphatidylcholine (PC) or DAG as donors of fatty acyl moieties to DAG. These reactions are catalyzed by phospholipid diacylglycerol acyltransferase (PDAT) or diacylglycerol transacylase (DGTA), respectively. Complementary DNAs (cDNAs) encoding PDAT have been isolated (Dahlqvist et al. 2000, Stahl et al. 

Mhaske, V., K. Beldjilali, J. Ohhogge, and M. Pollard. 2005. Isolation and characterization of an Arabidopsis thaliana knockout line for phospholipids diacylglycerol transacylase gene (At5gl3640). Plant Physiol Biochem. 43 413M17. 

A possible route for the reincorporation of phospholipid diacylglycerols is the pathway described by Kanoh and Ohno (1973) in which CDP-choline 1,2-. n-diacylglycerol transferase is reversed ... 

Hannun, YA, Loomis, CR and Bell, RM (1986) Protein kinase C activation in mixedmiceUes. Mechanistic implications of phospholipid, diacylglycerol, and calcium interdependencies. Journal of Biological Chemistry, 261, 7184-7190. 

In seed oils containing PUFAs and/or unusual fatty acids (such as ricin-oleic acid), however, a large proportion of the acyl chains used for TAG synthesis are actually derived from acyl chains which have been modified in the nitrogenous phospholipids (eg, phosphatidylcholine (PC)) in the ER. 5n-l,2-Diacylglycerol (DAG) formed via PAP action can be converted to PC via the catalytic action of phospholipid diacylglycerol cholinephosphotrans-ferase (PDCT) and/or choUnephosphotransferase (CPT). Once the DAG... 

---