Phosphate metabolism, calcium link

The metabolism of phosphate is closely linked to that c calcium. The factors which regulate calcium metabolism als influence phosphate metabolism. Among these factors are ... 

The metabolism of calcium is linked intimately with that of phosphate (Figure 49-23). " The homeostatic mechanisms are directed principally toward the maintenance of normal extracellular calcium and phosphate concentrations, which sustain the extracellular and intracellular processes and provide substrate for skeletal mineralization. The parathyroid gland responds to a decrease in free calcium concentration within seconds. During a time of calcium deprivation, the increase in serum PTH rapidly alters both renal and skeletal metabolism. 

Although phosphorus in the form of phosphate ions is essential for numerous body functions, its metabolism is intricately linked to that of calcium... 

---