6-Phenylhexanoic acid

Fig. 32. (a) Carboxypeptidase A substrate A-t-boc-phenylalanylphenylalanine (an arrow denotes the scissle peptide carbonyl) and (b) its ketomethylene analog, N (tert-butoxycarbo-nyl)-5-amino-2-benzyl-4-oxo-6-phenylhexanoic acid (BBP) (Shoham et al, 1988). 

FcHL log K 9.09. and 9 46 = FeOL " log K - 12 99, and -12 52 Wuh benzoic, I-naphthoic, 3.5 dihydroxybenzoic. and 6-phenylhexanoic acids, formation of surface complexes involving uvo (or three) molecules of organic acid per one adsorption site was considered... 

Fig. 8.4. Profiles of the heat effect observed for complexation reactions of y-CyD with (a) 4-phenylbutyric acid, (b) 5-phenylvaleric acid, and (c) 6-phenylhexanoic acid under comparable experimental conditions 2.7-2.9 mM y-CyD and 190-230 mM guest in the initial solutions).

Phenyl chloroformate, in C-00014 10-Phenyldecanoic acid, P-00066 6-Phenylhexanoic acid, P-00067... 

Phenylhexanoic acid Amide, in P-00067 C12H17NO3 >Cerulenin, C-00012 Ci2H 8... 

Epoxide 6.254 was condensed with the enolate anion of 6.255. In this case, high diastereoselectivity was achieved when alcohol 6.347 was produced in >90% yield. The high diastereoselectivity is due to using enantiopurc 6.254 as a chiral template and "equipping" 6.255 with the auxiliary shown. Amino-amide 6.256 (a derivative 5-amino-2-benzyl-4-hydroxy-6-phenylhexanoic acid) is an intermediate in a synthetic route to hydroxy ethylene dipeptide isostere inhibitors of HIV-1 protease. 

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