Phenyl-propanenitrile

Recently, almond meal was used for the resolution of rac-2-hydroxy-2-phenyl-propanenitrile. Under the optimized conditions, (S)-2-hydroxy-2-phenylpropaneni-trile, as the less reactive enantiomer, was obtained in 98-99% ee at approximately 50 % conversion11181. In a similar way the (S)-cyanohydrin was afforded from racemic 2-methyl-2-hydroxyhexanenitrile with P. amygdalus HNL in more than 90%... 

Methy-2-phenyl- propanenitrile CH3-C(CH3)(CN)C6Hs 59.9 250.6 Pyrolysis 1982MEO... 

Write an equation showing how you could prepare ethyl phenyl ketone from propanenitrile and a Grignard reagent What is the structure of the imine intermediate ... 

Propane, 2,2-dimethyl-l-phenyl-, 55, 112 Propane, 2 isocyano 2 methyl-, 55, 96 Propanenitrile, 2-(2-butylthioethenyl) 2,3, 3-tnphenyl- [Propiomtnle, 2-(2-butyl thiovinyl)-2,3,3-tnphenyl-[, 55, 102 Propanenitrile, 2-mellioxy inefhyl-2-phenyl-[Propiomtrile, 2-methoxymethyl-2-phenyl-], 55, 94... 

Propanenitrile, 2-(4-nitrophenyl>2-phenyl-[Propionitrile, 2-(4-mtrophenyl)-2-phenyl-], 55, 94... 

Whereas the rates of exchange (kex) and racemization (krac) for 2-methyl-3,3-diphcnyl-propanenitrile (k /krac 1.8)142 and phenyl 2,2-diphenylcyclopropyl ketone (kc /krac l)u3 144 are approximately equal in each case (total racemization), 2,2-diphenylcyclo-propanecarbonitrile (kC t./kraCi 12)145 preserves its optical activity with more than 99.9% retention. This finding confirms that the acidifying character of the cyano group is mainly inductive in nature, i.e., the anion retains its pyramidal structure. 

Propanenitrile, 3-(ethyl(3-methylphenyl)amino)-. See N-Cyanoethyl-N-ethyl-m-toluidine Propanenitrile, 3-( ethyl phenyl amino)-. See Cyanoethylethyl aniline Propanenitrile, 2-hydroxy-2-methyl-. See 2-Hydroxy-2-methylpropanenitrile Propanenitrile, 3-methoxy-. See 3-Methoxypropionitrile Propane, 2-nitro-. See2-Nitropropane Propaneperoxoic acid, 2-methyl-, 1,1-dimethylethyl ester. Seet-Butyl peroxyisobutyrate... 

Utilizing previously developed alkylation technology, the 2-alk>d-2-phenyl-3-(o-nitrophenyl)-propanenitriles shown in the equation below have become accessible. Reductive cyclization of these materials leads to substituted 3,4-dihydroquinolines or their N-oxides. 

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