Phenyl I-Butyl Ether

Dimethyl sulfoxide in synthesis of phenyl i-butyl ether, 46, 89 10,10-Dinitrocamphan-2-ol, 46, 56... 

The crude material also contains some polymeric material and traces of solvent. Gas chromatography indicates that the phenyl I-butyl ether is 60-70% pure at this point. 

Phenyl I-butyl ether is swirled with 6N hydrochloric acid until solution is completed. The solution is then saturated with sodium chloride and extracted with ether to yield phenol, identifiable as the tribromide. 

The procedure described here is based on a method outlined by Cram, Rickborn, and Knox.2 The method is not a general one for the preparation of a substituted phenyl I-butyl ether because an aryne intermediate is involved. It appears that aryl fluorides undergo direct substitution to yield unrearranged aryl... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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