Phenyl diphenylphosphinate esters

Another reaction performed in the dead-end reactor discussed before, is the allylic amination of 3-phenyl-2-propenyl-carbonic acid methyl ester with morpholine. [30] First and second generation commercially available DAB-dendrimers were functionalized with diphenylphosphine groups (Figure 4.13). Two different membranes were used, the Nadir UF-PA-5 (ultrafiltration) and the Koch MPF-50 (former SELRO) (nanofiltration), which gave retentions of 99.2% and 99.9% respectively for the second generation functionalized dendrimers. 

The effects of changes in structure, temperature, and reaction medium on the kinetics of alkaline hydrolysis of aryl esters of phosphinothioic acids (182 R = R = Me or Ph R = Me, R = Ph X = H, Br, Me, or NO2) have been investigated. The effect of the nature of the leaving group on the kinetics of alkaline hydrolysis of aryl diphenylphosphinates has also been reported on. Indirect evidence has been advanced for the participation of the azaphospholi-dines (183) in the solvolysis of A/-[amino(methyl)phosphinyl]-L-phenylalanine derivatives, and it includes the transfer of the P-amino group to the phenyl-alanyl carbonyl. The products from the hydrolysis or ammonolysis of fosfomycin have the threo structure and have been shown to possess no antibiotic activity. ... 

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