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Phenoxazinone synthetase

Table 8. Inhibition of phenoxazinone synthetase activity by compounds related to... Table 8. Inhibition of phenoxazinone synthetase activity by compounds related to...
Table 9. Natufe of the inhibition of phenoxazinone synthetase activity by o-aminobenzoic acid, m-aminophenol, 0- and m-anisidine... Table 9. Natufe of the inhibition of phenoxazinone synthetase activity by o-aminobenzoic acid, m-aminophenol, 0- and m-anisidine...
Table 13. Inhibition of phenoxazinone synthetase synthesis by chloramphenicol... Table 13. Inhibition of phenoxazinone synthetase synthesis by chloramphenicol...
Phenoxazinone synthetase, specific activity O.D. Units/ mg protein... [Pg.326]

The enzymatic synthesis of the actinomycin chromophore also has been described (Weissbach and Katz, 1961 Katz and Weissbach 1962 Salzman, Weissbach and Katz, unpublished results). An enzyme, designated phenoxa-zinone synthetase, was obtained from sonic extracts of S. antihioticus and was shown to catalyze the oxidative condensation of o-aminophenols to the corresponding phenoxazinone. When 3-hydroxy-4-methylanthranilic acid (4MHAA) was used as substrate, actinocin was synthesized. The enzyme has been purified approximately 25- to 30-fold from sonic or French pressure cell extracts of the organism by means of standard protein fractionation procedures (ammonium... [Pg.309]


See other pages where Phenoxazinone synthetase is mentioned: [Pg.88]    [Pg.126]    [Pg.127]    [Pg.162]    [Pg.163]    [Pg.310]    [Pg.312]    [Pg.316]    [Pg.317]    [Pg.318]    [Pg.319]    [Pg.326]    [Pg.88]    [Pg.126]    [Pg.127]    [Pg.162]    [Pg.163]    [Pg.310]    [Pg.312]    [Pg.316]    [Pg.317]    [Pg.318]    [Pg.319]    [Pg.326]    [Pg.337]    [Pg.161]   
See also in sourсe #XX -- [ Pg.88 ]

See also in sourсe #XX -- [ Pg.162 , Pg.163 ]




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Phenoxazinone

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