Phencyclidine adverse effects

Dextromethorphan is metabolized by CYP2D6 to dex-trorphan, which binds to phencyclidine receptors and is thought to account for the toxic effects of hallucinations, tachycardia, hypertension, ataxia, and nystagmus. Individuals who are slow metabolizers, those who take long-acting dextromethorphan formulations, and those who take serotonin re-uptake inhibitors or MAO inhibitors are at increased risk of adverse effects. 

Phencyclidine (PCP), commonly referred to as angel dnst and crystal, was popular in the 1970s, bnt as its adverse effects became better known, use declined. PCP is most often a substitnte for or contaminant of other dmgs, and its most common pattern of nse may now... 

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