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Pharmacological space

Sir lames Black s (Nobel Laureate in Physiology and Medicine, [Pg.521]

Will it be possible to confirm laboratory-specificity in humans  [Pg.521]

Is a clinical condition relevant to the specificity mentioned in point four  [Pg.521]

Does the project have a champion - someone with the necessary passion, conviction and energy  [Pg.521]

At the invention of modem dmg discovery, Paul Ehrlich screened just over 600 synthetic compounds to discover arsphenamine (Salvarsan), a novel treatment for syphilis. With advances in screening technology, researchers can now routinely test millions of compounds in protein-based [Pg.521]

Paolini G, Shapland R, van Hoorn W, Mason J, Hopkins A (2006) Global mapping of pharmacological space. Nat Biotechnol 24 805-815... [Pg.79]

Paolini GV, Shapland RHB, van Hoorn WP, Mason IS, Hopkins AL. Global mapping of pharmacological space. Nature Biotechnol. 2006 24 805-815. [Pg.223]

I would like to thank Gaia Paolini, Colin Groom, Carolyn Barker, Mike Snarey, Bissan Al-Lazikani and John Overington for all their efforts to understand pharmacological space. [Pg.531]

See other pages where Pharmacological space is mentioned: [Pg.152]    [Pg.23]    [Pg.52]    [Pg.42]    [Pg.266]    [Pg.276]    [Pg.292]    [Pg.294]    [Pg.318]    [Pg.245]    [Pg.146]    [Pg.218]    [Pg.194]    [Pg.154]    [Pg.227]    [Pg.519]    [Pg.520]    [Pg.521]    [Pg.521]    [Pg.521]    [Pg.522]    [Pg.524]    [Pg.526]    [Pg.528]    [Pg.530]    [Pg.531]    [Pg.531]    [Pg.532]    [Pg.17]    [Pg.204]    [Pg.36]    [Pg.215]    [Pg.18]    [Pg.29]    [Pg.334]    [Pg.227]    [Pg.519]    [Pg.520]    [Pg.521]    [Pg.521]    [Pg.521]    [Pg.522]    [Pg.524]    [Pg.526]    [Pg.528]   
See also in sourсe #XX -- [ Pg.146 ]

See also in sourсe #XX -- [ Pg.15 ]



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