Marijuana pharmacokinetics

Barnet G, Licko Y and Thompson T (1985). Behavioural pharmacokinetics of marijuana. 

Barnett G, Licko V, Thompson T. (1985). Behaviorai pharmacokinetics of marijuana. Psychopharmacology (Berlin). 85(1) 51-56. 

The effects of smoked marijuana (3.95% tetrahydrocannabinol up to three cigarettes per day) and oral dronabinol (2.5 mg tds) on the pharmacokinetics of indinavir 800 mg 8-hourly (n = 28) have been evaluated in a randomized, placebo-controlled study in HIV-infected patients (148). On day 14, marijuana reduced the 8-hour AUC of indinavir by 15%, the Cmax by 14%, and the Cm n... 

Cannabis in the New World Committee Reports on Marijuana Epidemiology Methods of Use Active Ingredients Pharmacokinetics Absorption... 

The most abundant member of this group is the cannabinoid Al-THC-7-oic-acid. When tested in humans as well as in the rhesus monkey, this cannabinoid did not show the behavioral activity or the cardiovascular effects characteristic of the parent substance, THC. (Perez-Reyes, M. In Pharmacokinetics and Pharmacodynamics of Psychoactive Drugs, Barnett, G. and Chiang, N. (eds), Biomedical Press, 1985, pages 287-310 Mechoulam, R. and Edery, M. ln Marijuana, Mechoulam, R. (ed.), Academic Press, New York, 1973). Thus, little attention has been given to the possible pharmacodynamic properties of this metabolite or any of the other acid metabolites of THC. 

Keywords Cannabinoids Pharmacokinetics Tetrahydrocannabinol Cannabidiol Absorption Distribution Metabolism Excretion Interpretation Oral fluid Sweat Hair Plasma Urine Alternate matrix Marijuana... 

AgureU S, Gillespie H, HaUdin M, HoUister LE, Johansson E, Lindgren JE, Ohlsson A, Szirmai M, Widman M (1984) A review of recent studies on the pharmacokinetics and metabolism of delta-l-tetrahydrocannabinol, cannabidiol and cannabinol in man. In Paton SW, Nahas GG (eds) Marijuana 84. IRL Press, Oxford, pp 49-62... 

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