Pharmacodynamics data analysis

Gabrielsson J and Weine, D. Pharmacokinetic and pharmacodynamic data analysis concept and applications, 3rd Edition. Stockholm Swedish Pharmaceutical Society, 2000. 

Gabrielsson, J., Weiner, D., in Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Applications, 2nd edition. Swedish Pharmaceutical Society, Swedish Pharmaceutical Press, Stockholm, 1997, pp. 412-418. 

Gabrielsson, J. and Weiner, D., Methodology for pharmacoki-netic/pharmacodynamic data analysis, Pharmaceutical Science and Technology Today, Vol. 2, No. 6, 1999, pp. 244-252. 

Gabrielsson J, Weiner D. 2000. Pharmacokinetic and pharmacodynamic data analysis, concepts and applications. 3rd ed. Stockholm (SE) Swedish Pharmaceutical Press. 

This approach is called the first order (FO) method in NONMEM. This is the most widely used approach in population pharmacokinetic and pharmacodynamic data analysis, and has been evaluated by simulation. The use of the first-order Taylor series expansion to approximate the non-linear model in r], and, possibly,... 

Gabrielsson JL, Weiner DL. Methodology for pharmacokinetic/pharmacodynamic data analysis. Pharm Sci Technol Today. 1999 2(6) 244-252. 

Gabrielsson, J., and D. Weiner. 1997. Pharmacokinetic/pharmacodynamic data analysis Concepts and applications. Stockholm, Sweden Swedish Pharmaceutical Press. 

Gahrielsson J and Weiner D (2001) Pharmacokinetic and Pharmacodynamic Data Analysis concepts applications, 3rd edn, pp. 175-3195. Kristianstads Boktryckeri AB, Stockholm Taylor and Francis. 

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