Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Pharmaceuticals drug-like heterocycles

Nucleophilic phosphine organocatalysis A practical synthetic strategy for the drug-like nitrogen heterocyclic fiamework construction 13MRM836. One-pot synthesis and its practical appHcation in pharmaceutical industry 12COS873. [Pg.256]

Like piperidine, morpholine is used in pharmaceuticals as a secondary amine component. One of the drugs derived from morpholine as a heterocycle is viloxazine 5, which can be obtained from 4 by reaction with ethanolamine hydrogensulfate. Structurally related to 5 is reboxetine 6 (in the form of the ( S, 5)-(+)-stereoisomer). Both 5 and 6 are effective as antidepressants. [Pg.382]

Properties Colorless liq., brandy-like odor, sweet si. fruity flavor sol. in alcohol insol. in water m.w. 158.20 dens. 0.9697 b.p. 84.5 C (11 mm) flash pt. 173 F ref. index 1.4219 Uses Synthesis of heterocyclics (furanes, pyrazolones, isoxazoles, pyrimidines), drugs synthetic flavoring agent in foods and pharmaceuticals Features Fruity flavor... [Pg.2198]

See other pages where Pharmaceuticals drug-like heterocycles is mentioned: [Pg.50]    [Pg.31]    [Pg.319]    [Pg.47]    [Pg.316]    [Pg.100]    [Pg.336]    [Pg.309]    [Pg.277]    [Pg.120]    [Pg.4499]    [Pg.4500]    [Pg.5928]    [Pg.291]    [Pg.291]   
See also in sourсe #XX -- [ Pg.143 ]



SEARCH



Drug-like

Drug-like heterocycles

Drug-likeness

Heterocycles drugs

Heterocyclic Drugs

Pharmaceutical drugs

© 2024 chempedia.info