Pharmaceuticals Cannabis sativa

Dronabinol (46) and cannabidol (47) (Sativex GW Pharmaceuticals, 2005), as a mixture formulation named as Sativex (tradename), the world s first pharmaceutical prescription medicine derived from the cannabis plant Cannabis sativa The drug (a mixture of dronabinol (46) and... 

SOURCE K.H. Davis et al., "The Preparation and Analysis of Enriched and Pure Cannabinoids from Marihuana and Hashish," Uoydia 33 (1970) 453 F. Merkus, "Cannabivarin and Tetrahydrocannabivarin, Two Constituents of Hashish," Nature 232 (19711 579 P.S. Fetternrwn et al., "Mississippi Grown Cannabis sativa L.," Journal of Pharmaceutical Science 60 (1971) 1246 P. Chambon et al., "Problemes Poses Par la Culture Locale du Chanvre et Dosage des Chanvre," Bulletin des Traveaux de la Societa de Pharmacia da Lyon 16 (1972) 46. 

J.W. Fairbaim et al., The Stability of Cannabis and its Preparations on Storage, Journal of Pharmacy and Pharmacology 28 (1976) 1 C.E. Turner et al., Constituents of Cannabis Sativa L. IV Stability of Can-nabinoids in Stored Plant Material, Journal of Pharmaceutical Science 62(1973) 1601. 

C .E. Turner et al., Isolation of Cannabisatavine, an Alkaloid From Cannabis Sativa L. Root, Journal of Pharmaceutical Science 65 (1976) 1084 The Isolation and Characterization of the Alkaloid Can-nabisativine From the Leaves of a Thailand Variant of Cannabis Sativa L., U.N. Secretariat Document ST/SOA/Serv S/52 (1975) F. Klein and H. Rapoport, Cannabis Alkaloids, Nature 232 (1971) 258 ... 

Paracelsus, often regarded as the father of alchemy, first became acquainted with Cannabis products while in Basel, Switzerland, where the pharmaceutical firm of Sandoz now stands. It was also there that the botanist Leonhardt Fuchs sketched a charming, classic drawing of the sativa plant in 1543- By this time, the inebriating effects of sativa % resin had been discovered by Europeans. Francois Rabelais, writing in the early sixteenth century devoted three small chapters of his Third Book of Pantegruel to this herb s botanical and psychoactive properties. 

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