Phanerochaete chrysosporium compounds

Servent D, C Ducrorq, Y Henry, A Guissani, M Lenfant (1991) Nitroglycerin metabolism by Phanerochaete chrysosporium evidence for nitric oxide and nitrite formation. Biochim biophys Acta 1074 320-325. Spain JC (1995a) Biodegradation of nitroaromatic compounds. Annu Rev Microbiol 49 523-555. 

Figure 1. 3-0-4 lignin substructure model compounds and products of their degradation by ligninolytic cultures of Phanerochaete chrysosporium and by lignin peroxidase. D H, and 0 of 3-ether bond and of H2 0, respectively. B and C show results of stable isotope experiments. 

Lignin peroxidase of Phanerochaete chrysosporium catalyzes the ring cleavage of /3-0-4 lignin substructure model compounds and synthetic lignin (DHP). A mechanism for the ring cleavage by the enzyme is described. 

Harper DB, McRoberts WC, Kennedy JT (1996) Comparison of the Efficacies of Chloro-methane, Methionine, and S-Adenosylmethionine as Methyl Precursors in the Biosynthesis of Veratryl Alcohol and Related Compounds in Phanerochaete chrysosporium. Appl Environ Microbiol 62 3366... 

An example of cometabolism of pollutants is provided by the white rot fungus Phanerochaete chrysosporium, which degrades a number of kinds of organochlorine compounds, including DDT, PCBs, and chlorodioxins, under the appropriate conditions. The enzyme system responsible for this degradation is one that the fungus uses to break down lignin in plant material under normal conditions. 

Ferapontova EE, Castello J, Gorton L (2006) Bioelectrocatalytic properties of lignin peroxidase from Phanerochaete chrysosporium in reactions with phenols, catechols and lignin-model compounds. Biochim Biophys Acta 1760 1343-1354... 

Wariishi H, Valli K, Renganathan V et al (1989) Thiol-mediated oxidation of nonphenolic lignin model compounds by manganese peroxidase of Phanerochaete chrysosporium. J Biol Chem 264 14185-14191... 

The white rot basidiomycete Phanerochaete chrysosporium secretes two soluble H202-requiring peroxidases which are Involved in lignin degradation. Both lignin peroxidase (LIP) and manganese peroxidase (MnP) form the oxidized intermediates compound 1 and compound II. 

Scheme 1. Model compounds are being used to elucidate the specific reactions of lignin decomposition by white-rot fungi. The fate of a nonphenolic dia l-propane-tupe of model in ligninolutic cultures of Phanerochaete chrysosporium Burds is shown (113-15).

U Tuor, H Wariishi, HE Schoemaker, MH Gold. Oxidation of phenolic arylglycerol beta-aryl ether lignin model compounds hy manganaese peroxidase from Phanerochaete chrysosporium. Oxidative cleavage of an alpha-carhonyl model compound. Biochemistry 31 4986 995, 1992. 

Particular attention has been focused on the white-rot fungus Phanerochaete chrysosporium because of its ability to degrade lignin and to metabolize a wide range of unrelated compounds including PAHs (Bumpus 1989) and... 

In view of current interest in the persistence of recalcitrant organochlorine compounds, it is appropriate to note the degradation of 2,7-dichlorobenzo-1,4-dioxin by Phanerochaete chrysosporium (Valli et al. 1992a). Degradation involves dechlorination and ring scission as the initial reactions (Figure 6.61) ... 

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