PGD 11-ketoreductase

PGD2 may undergo two additional reactions, which are illustrated in Figure 4.9. It may be converted into PGF2 by the enzyme PGD 11-ketoreductase, a cytosolic protein that requires reduced pyridine nucleotides (NADPH) for activity. The high levels of PGD 11-ketoreductase in liver tissue suggests that the main role... 

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