Peroxidase-cyclooxygenase superfamily cyclooxygenases

Fig. 2.2 Phylogenetic relationships within the peroxidase-cyclooxygenase superfamily. This circle tree was obtained in MEGA package [13] after compressing all resolved branches from 160 full sequences of this superfamily to main clades. Seven subfamilies [10] are clearly discernible...

Bacterial members represent the most ancient forms of the peroxidase-cyclooxygenase superfamily that probably remained without significant changes during the... 

Fig. 2.3 Phylogeny of bacterial representatives of the peroxidase-cyclooxygenase superfamily. The reconstructed tree obtained from the NJ-method of the MEGA package [13] with JTT matrix and 1,000 bootstrap replications is presented. A similar tree was obtained also with ProML-method of the PHYLIP package [16] with 100 bootstraps. Numbers in the nodes indicate bootstrap values for NJ and ProML method, respectively. Abbreviations of protein names correspond to PeroxiBase...

Zamocky M, Jakopitsch C, Furtmiiller PG et al (2008) The peroxidase-cyclooxygenase superfamily reconstructed evolution of critical enzymes of the innate immune system. Proteins 72 589-605... 

---